TABLE 5.
Hepatic specificity of xenoantibodies in sera of liver recipients by indirect immunofluorescencea
| Treatment | 7–8 Days after transplantation | 30–40 Days after transplantation | ||
|---|---|---|---|---|
| Sinusoids | Large vessel endothelium | Sinuosids | Large vessel endothelium | |
| FK506 1.0 mg/kg | +++ | +++ | ± | ± |
| ++ | ++ | ± | ± | |
| FK506 1.0 mg/kg + RS-61443 20 mg/kg (0–13) | ++ | ++ | ± | ± |
| ++ | ++ | ± | ± | |
| FK506 1.0 mg/kg + BQR 3.0 mg/kg (0–13) | + | + | ± | ± |
| + | + | ± | ± | |
Immunofluorescent intensity was scored on a qualitative scale from 0 to 3+; values were shown as IgM deposits.