Table 1.

Performance characteristics of various approaches for the evaluation of hyperprolactinemia following PEG-precipitation.

Method	Sensitivity (%)	95% CI (%)	Specificity (%)	95% CI (%)	Efficiency * (%)
Standard reference interval (≤19 ng/mL)	59	33–81	100	72–100	77
Post-PEG modified reference range (≤13 ng/mL)	88	62–98	85	54–97	87
GFC regression estimate with use of the standard reference interval (≤19 ng/mL)	82	56–95	85	54–97	83
Post-PEG cutoff determined by ROC analysis (≤11.6 ng/mL)	94	71–99	85	55–98	90

^*Percent correctly classified ([true positives + true negatives])/total # of patients)