Figure 3.

Nf1 OPG mice have no abnormalities in sensorimotor function or visual impairment. (A) Walking initiation is unaffected in Nf1 OPG mice. (B) Nf1 OPG mice were not impaired relative to littermate control (CT) mice on the small platform (balance) test. (C) There were no differences between littermate control (CT) and Nf1 OPG mice on the inverted screen test, suggesting that grip strength was intact in Nf1 OPG mice. Nf1 OPG mice performed equivalently to littermate control (CT) mice on rotarod tests of balance and dexterity involving (D) constant and (E) accelerating speeds. (F) No significant differences between littermate control (CT) and Nf1 OPG mice were observed using VOS to measure visual acuity (P = 0.96).