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Nf1+/− dopaminergic neurons have reduced neurite lengths and smaller growth cone areas. (A) TH-immunoreactive neurons from the ventral midbrain of E13 wild-type (WT) and Nf1+/− mice. (B) Nf1+/− TH-immunoreactive neurons have shorter neurite lengths compared with WT controls (P = 0.001; n = 30). (C) Nf1+/− TH-immunoreactive neurons have smaller growth cone areas relative to WT controls (P = 0.001; n = 30). Scale bars = 50 µm.
