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. 2010 Jul 1;299(4):G855–G866. doi: 10.1152/ajpgi.00434.2009

Table 2.

Basic physical and biochemical data

Group Caloric Intake, kcal·day−1·mouse−1 Weight, g Glucose, mg/dl Cholesterol, mg/dl TG, mg/dl AST, U/l ALT, U/l Insulin, ng/ml Leptin, ng/ml Adiponectin, μg/ml HOMA-IR
Control 12.28 ± 1.54 26.7 ± 0.3 137 ± 15 69.6 ± 6.2 51.8 ± 3.1 37.8 ± 2.4 8.8 ± 1.8 0.087 ± 0.011 0.86 ± 0.17 9.94 ± 0.733 0.28 ± 0.04
EtOH
    10% 12.83 ± 0.63 26.4 ± 0.5 112 ± 13 83.1 ± 5.7 67.4 ± 9.6 43.0 ± 8.4 14.6 ± 3.9 0.11 ± 0.020 2.42 ± 0.19f 9.77 ± 1.217 0.36 ± 0.07
    14% 13.44 ± 0.65 24.3 ± 0.5b 143 ± 9 68.6 ± 4.2 64.7 ± 6.0 48.8 ± 10.5 12.5 ± 2.4 0.13 ± 0.010c 1.84 ± 0.38b 13.39 ± 0.735b 0.45 ± 0.05d
    18% 15.24 ± 1.36 25.5 ± 0.5 108 ± 7 64.0 ± 5.2 86.0 ± 9.4b 46.6 ± 10.9 10.0 ± 2.0 0.17 ± 0.010f 3.66 ± 0.98c 13.06 ± 0.976c 0.56 ± 0.05f
HFD 18.53 ± 2.73a 36.6 ± 1.2d 220 ± 10d 104 ± 7.3e 77 ± 9.2c 41.4 ± 4.8 7.8 ± 1.2 0.13 ± 0.02f 49.6 ± 11.3d 12.06 ± 0.863a 0.50 ± 0.08c
db/db 18.11 ± 1.04c 51.4 ± 0.8d 120 ± 10 182 ± 6d 59 ± 16 57.2 ± 7.4b 102 ± 22d 2.41 ± 0.69d 1145 ± 486b 8.32 ± 0.930 7.35 ± 2.19e
ob/ob 20.57 ± 1.54d 61.8 ± 0.6d 155 ± 9 194 ± 7d 83 ± 8d 54.0 ± 4.4e 99 ± 7d 1.48 ± 0.46b 0.44 ± 0.09 11.77 ± 0.875 4.95 ± 1.57d

Values are means ± SE. EtOH, ethanol; TG, triglyceride; HFD, high-fat diet; AST, aspartate aminotransferase; ALT, alanine aminotransferase; HOMA-IR, homeostasis model assessment of insulin resistance.

a

0.1 > P > 0.05,

b

P < 0.05,

c

P < 0.025,

d

P < 0.01,

e

P < 0.005,

f

P < 0.001 vs. control.