Table 1.
Subject | Description of the Assumption |
---|---|
Heart geometry | |
1.1 | Represented by a prolate spheroid (57) |
Network partitioning | |
2.1 | Hierarchical design (9, 31, 35, 58, 68) |
2.2 | Epicardial subnetworks: orders −12 to −9 (9, 31, 35, 68) |
2.3 | Transmural subnetworks: orders −8 to −5 (35) |
2.4 | Perfusion subnetworks: capillaries of orders −4 to 0v (31, 35) |
Network design | |
3.1 | The network has a tree-like structure (37) |
3.2 | Veins accompany their arterial counterparts (18, 27, 33) |
3.3 | Ratios of 1.61:1 and 1.86:1 are maintained, on average, between the venous (0v) and arterial (0a) capillaries for the venous LAD, LCx, and RCA, respectively (7, 37) |
3.4 | Venules and venous capillaries can run obliquely between parallel sheets (4, 49) |
3.5 | Arterial major branches are drained only by their venous counterparts, i.e., there is no communication between major branches, neither arterial nor venous |
3.6 | No arcading or anastomoses in the venous network |
Network morphometry | |
4.1 | No correlation between successive segment lengths and diameters |
Three-dimensional reconstruction scheme | |
5.1 | Relation between diameter asymmetry (34) and branching angles: the higher the diameter asymmetry, the larger the asymmetry in the branching angle (9, 17, 18, 29, 68) |
5.2 | Functional capillaries are oriented along the direction of the myocytes (9, 17, 18, 29, 49, 68) |
5.3 | Perfusion and transmural venous vessels can cross each other and arterial vessels as well (4, 30, 45) |
LAD, left anterior descending coronary artery; LCx, left circumflex artery; RCA, right coronary artery.