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. 2010 Jul 23;299(4):H1100–H1108. doi: 10.1152/ajpheart.00084.2010

Fig. 4.

Fig. 4.

MLC2A mice exhibit improved cardiac function after ischemia compared with SUR2 null mice. Left ventricular developed pressure (LVdevP) was measured with a pressure-sensing catheter attached to a fluid-filled balloon placed inside the left ventricle. Baseline parameters were similar for all cohorts. A: isolated hearts from MLC2A mice (n = 5) exhibited increased LVdevP after ischemia compared with hearts from SUR2 null mice (n = 10). *P < 0.05. B: systolic pressure was similar between cohorts. C: diastolic pressure was significantly reduced in isolated hearts from MLC2A mice compared with SUR2 null and MLC2A Line 8 isolated hearts. *P < 0.01 vs. SUR2 null baseline LVdevP; #P < 0.001 vs. SUR2 null.