Table 3.

Serum hormone and substrate concentrations following LFD, HFD, and pair feeding of the HFD isocaloric to LFD calories

	LFD		HFD		Pair-Fed HFD
	OP	OR	OP	OR	OP	OR
Glucose, mM
Female*	13.6 ± 0.6	12.3 ± 0.7	15.1 ± 0.9	16.3 ± 1.1	11.2 ± 0.2	9.7 ± 0.5
Male*†	16.5 ± 0.8	13.3 ± 0.6	19.0 ± 1.6	15.0 ± 1.0
Insulin, ng/ml
Female*†	4.2 ± 0.6	2.0 ± 0.5	7.6 ± 0.8	3.6 ± 0.9	4.8 ± 0.5	3.7 ± 0.6
Male	4.4 ± 1.1	3.5 ± 0.6	5.2 ± 0.9	5.3 ± 0.9
Leptin, ng/ml
Female*†	3.3 ± 1.1	1.2 ± 0.2	7.8 ± 0.9	3.4 ± 1.0	6.5 ± 1.4	1.6 ± 0.2
Male*†	5.5 ± 1.0	2.3 ± 0.3	13.4 ± 1.9	13.4 ± 1.9
Triglyceride, mg/dl
Female†	38.9 ± 17.0	64.8 ± 15.5	117.6 ± 11.9	86.1 ± 12.7	49.0 ± 10.3	27.7 ± 2.2
Male*†	257.4 ± 40.2	125.1 ± 13.7	368.1 ± 37.9	214.5 ± 17.9

Values presented are means ± SE; n = 8 rats/phenotype. Within-gender main effects are provided in the first column

^*Phenotype effect {obesity prone (OP) vs. obesity resistant (OR)}.

^†Diet effect (LFD vs. HFD), P < 0.05. No across- or within-phenotype differences were present for any of the parameters. Across-gender analyses were not performed. Pair feeding was not performed in male rats.