Table 5.

MultiRTA leave-one-allele-out prediction results for the DFRMLI compilation of experimental binding data for overlapping peptides from four different antigens

MHC allotype	AUC (± 95% CI)	Number of binders
DRB1*0101	0.798 (± 0.096)	23
DRB1*0301	0.659 (± 0.177)	11
DRB1*0401	0.787 (± 0.104)	22
DRB1*0701	0.797 (± 0.092)	17
DRB1*1101	0.772 (± 0.100)	29
DRB1*1301	0.722 (± 0.361)	2
DRB1*1501	0.639 (± 0.143)	15

The data set for each allotype contains 103 peptides with measured binding affinities. The 95% confidence intervals for AUC were calculated from the standard deviation of the linearly related Somer's D_xy statistic (${\sigma }_{\text{AUC}}=\frac{1}{2}{\sigma }_{Dxy}$) using the Hmisc package in R. Data sets with fewer binders have corresponding higher uncertainty in their AUC values.