Table 4. Numbers (%) of shared and unique MLVA9-UTRECHT types (MTs) in the four groups of clinical sources compared to the numbers of expected values based on 100.000 permutations (median, range and 95% confidence interval (CI)) when assuming random distribution of types.
MTs shared (percentage of total MTs) [95% CI] | |||||||
Unique | CF | ICU-I | ICU-2 | HA | CA | ||
Source | group I | group IIa | group IIb | group III | group IV | ||
CF | Observed | 64 (89%) | 6 (8%)a | 2 (3%) a | 0 a | 0 a | |
Expected | 58 [50–66] | 18 [13]–[23] | 13 [8]–[18] | 8 [4]–[12] | 4 [1]–[7] | ||
ICU-1 | Observed | 72 (88%) | 6 (7%) a | 3 (4%) a | 0 a | 0 a | |
Expected | 74 [66–82] | 18 [12]–[23] | 15 [10]–[20] | 9 [5]–[13] | 5 [2]–[8] | ||
ICU-2 | Observed | 58 (92%) b | 2 (3%) a | 3 (5%) a | 0 a | 0 a | |
Expected | 46 [38–53] | 13 [8]–[18] | 15 [10]–[20] | 7 [3]–[11] | 3 [1]–[7] | ||
HA | Observed | 30 (91%) b | 0 a | 0 a | 0 a | 3 (9%) | |
Expected | 23 [17]–[28] | 8 [4]–[12] | 9 [5]–[13] | 7 [3]–[11] | 2 [0–5] | ||
CA | Observed | 14 (82%) | 0 a | 0 a | 0 a | 3 (18%) | |
Expected | 10 [6]–[14] | 4 [1]–[7] | 5 [2]–[8] | 3 [1]–[7] | 2 [0–5] |
CF: cystic fibrosis patients, ICU: intensive care unit patients, HA: non-CF, non-ICU patients with hospital acquired P. aeruginosa, CA: non-CF, non-ICU patients with community acquired P. aeruginosa.
: value lower than expected within 95% CI range, i.e. less overlap of types between sources than in the case of random distribution of types.
: more unique genotypes per source than expected, i.e. high level of source-specificity rather than random distribution.