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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Pharm Res. 2010 Apr 13;27(11):2356–2364. doi: 10.1007/s11095-010-0119-5

Table 2.

Influence of Pluronic Polymers on Triclosan Solubility and Particle Size. Micelle Formulations Were Prepared Using Direct Dissolution Method. Data were expressed as mean ± SD, n=3.

Pluronic copolymers Average Molecular Weight* Average No. of EO/PO/EO units** HLB* Triclosan Solubility (mg/mL) Particle Size (nm) PDI
P123 5750 39/69/39 8 12.9±0.6 53.0±5.0 0.27
F127 12600 200/65/200 24 11.5±1.3 43.6 ±8.4 0.25
*

The average molecular weights and HLB values were determined and provided by the manufacturer (BASF, Wyandotte, MI).

**

The average numbers of EO and PO units were calculated using the average molecular weights of the Pluronics.