Table 2.
Influence of Pluronic Polymers on Triclosan Solubility and Particle Size. Micelle Formulations Were Prepared Using Direct Dissolution Method. Data were expressed as mean ± SD, n=3.
| Pluronic copolymers | Average Molecular Weight* | Average No. of EO/PO/EO units** | HLB* | Triclosan Solubility (mg/mL) | Particle Size (nm) | PDI |
|---|---|---|---|---|---|---|
| P123 | 5750 | 39/69/39 | 8 | 12.9±0.6 | 53.0±5.0 | 0.27 |
| F127 | 12600 | 200/65/200 | 24 | 11.5±1.3 | 43.6 ±8.4 | 0.25 |
The average molecular weights and HLB values were determined and provided by the manufacturer (BASF, Wyandotte, MI).
The average numbers of EO and PO units were calculated using the average molecular weights of the Pluronics.