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. 2010 Oct 18;341:c5462. doi: 10.1136/bmj.c5462

Table 3.

 Intention to treat analysis. Values are numbers (percentages) unless stated otherwise

Control (high flow oxygen) Active (titrated oxygen) Treatment effect P value
Mortality
All patients 21/226 (9) 7/179 (4) 0.42 (0.20 to 0.89)* 0.02
Confirmed COPD 11/117 (9) 2/97 (2) 0.22 (0.05 to 0.91)* 0.04
Incidence of ventilation
All patients 19/213 (9) 13/166 (8) 0.88 (0.45 to 1.72)* 0.70
 Non-invasive ventilation 7 8
 Invasive ventilation 12 5
Confirmed COPD 15/105 (14) 8/84 (10) 0.67 (0.29 to 1.54)* 0.34
 Non-invasive ventilation 6 5
 Invasive ventilation 9 3
Length of hospital stay (mean (SD) days)
All patients 5.9 (5.6) (n=226) 5.5 (5.9) (n=179) −0.45 (0.57)† 0.19
Confirmed COPD 6.3 (5.8) (n=117) 5.4 (4.1) (n=97) −0.88 (0.70)† 0.37
Arterial blood gases (<30 min) (confirmed COPD patients)
Mean (SD) pH 7.29 (0.14) (n=19) 7.35 (0.16) (n=19) 0.06 (0.05)† 0.11
Mean (SD) carbon dioxide (mm Hg) 77.8 (49.2) (n=20) 54.7 (31.1) (n=20) −23.1 (13.0)† 0.06
Mean (SD) bicarbonate (mmol/l) 32.3 (10.1) (n=19) 26.8 (6.5) (n=19) −5.5 (2.76)† 0.07
Mean (SD) oxygen (mm Hg) (arterial only) 98.4 (46.1) (n=14) 79.3 (24.9) (n=9) −19.1 (16.8)† 0.34

COPD=chronic obstructive pulmonary disease.

*Relative risk (95% CI).

†Mean difference (SE).