Figure 8.
Effect of testosterone on myocardial antioxidant MnSOD mRNA (A) and protein (B) after I/R. N=4-9/group, Mean ± SEM, *p<0.05, **p<0.01 vs. male, #p<0.05, ##p<0.01 vs. castrated male. C. Schematic demonstrating the testosterone-regulated PI3K/Akt pathway and downstream signals in response to ischemia/reperfusion. AR: androgen receptor