Table 2.
Characteristics of H. influenzae meningitis cases from Salvador, Brazil, according to serotype.
| Characteristics | Type b (n=530) | Type a (n=28) | Other types (n=15)a | |||
|---|---|---|---|---|---|---|
| No. Responsesb | N (%) or median (IQR) | No. Responsesb | N (%) or median (IQR) | No. Responsesb | N (%) or median (IQR) | |
| Male sex | 527 | 301 (57) | 28 | 18 (64) | 15 | 8 (53) |
| Age <5 years | 520 | 473 (91) | 28 | 24 (86) | 15 | 4 (27)c |
| <2 years | 520 | 327 (63) | 28 | 14 (50) | 15 | 3 (20)c |
| 2–4 years | 520 | 146 (28) | 28 | 10 (36) | 15 | 1 (7) |
| CSF examinationd | ||||||
| Cells (×103/mm3) | 525 | 5.8 (2.2–10.0) | 28 | 8.4 (1.5–10.0) | 13 | 6.6 (2.8–8.6) |
| Glucose (mg/dL) | 529 | 20 (20–35) | 28 | 20 (20–30) | 15 | 20 (20–38) |
| Protein (mg/dL) | 529 | 300 (200–400) | 28 | 290 (185–500) | 15 | 300 (180–400) |
| Outcome | ||||||
| Neurological deficite | 481 | 70 (15) | 28 | 4 (14) | 15 | 1 (7) |
| ICU admission | 504 | 108 (21) | 28 | 4 (14) | 14 | 4 (29) |
| Death | 518 | 88 (17) | 28 | 4 (14) | 14 | 0 (0) |
NOTE: IQR, interquartile range; CSF, cerebrospinal fluid.
a
Includes 15 meningitis cases due to H. influenzae non-capsulated (9) type e (3) and type f (3) strains.
b
Number for which information was obtained.
c
Significant difference (P value <0.01) when compared with H. influenzae type b meningitis cases.
d
Initial examination performed during hospital admission.
e
Neurological deficit on discharge among survivors included ataxia (34 cases, all serotype b), motor deficit (16 cases, serotype b [15] and other type [1]), auditory deficit (9 cases, serotype b [6] and a [3];), hydrocephalus (7 cases, serotype b [6] and a [1]), and others (9 cases, all serotype b).