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. Author manuscript; available in PMC: 2011 Nov 5.
Published in final edited form as: J Mol Biol. 2010 Sep 21;403(4):505–515. doi: 10.1016/j.jmb.2010.09.014

Table 2.

Equilibrium dissociation constants of the Pol λ•DNA complex at 37 °C.

Enzyme KdDNA (nM)
WT 110 ± 20
R386A 90 ± 20
R386E 300 ± 100
R420A 200 ± 100
K422A 150 ± 40
Y505G 150 ± 70
Y505A 150 ± 50
F506A 140 ± 40
A510E 120 ± 60
R514A 70 ± 10
R517A 80 ± 30
R386A/A510E 120 ± 40
R386A/R514A 80 ± 30