Table 3.
Effect of postnatal THIM treatment on MOR density in the caudate putamen (CPU) and the dentate gyrus (DG) areas in 20-week old rats
| Hg dose (μg/kg) | CPU | DG | ||||||
|---|---|---|---|---|---|---|---|---|
| AV-AF | ±SEM | P | % CTRL | AV-AF | ±SEM | P | % CTRL | |
| 0 | 3.583 | 0.456 | 100 | 1.655 | 0.612 | 100 | ||
| 1,440 | 3.835 | 0.913 | n.s. | 107 | 1.117 | 0.444 | 0.02 | 67 |
| 3,000 | 8.301 | 2.553 | 0.02 | 232 | 0.307 | 0.132 | 0.005 | 18 |
AV-AF Average stained area fraction (% of the area), % CTRL percent of control value, P significancy. Neonatal rats’ exposure to THIM doses 1,440 and 3,000 μg/kg causes increase in MOR density in the CPU, but decrease in DG area. Statistical analysis is described in the “Results” section