Table 2.

Serum phosphorus: values at baseline and at week 25, changes from baseline, area under the curve (AUC) until Week 25, number of visits where target serum phosphorus (sP) was reached and time to reach target values

Parameter	CaMg		Sevelamer-HCl		P-value
	N	(Mean ± SD)	N	(Mean ± SD)
Serum phosphorus (mmol/L)a
Baseline	105	2.464 ± 0.4930	99	2.480 ± 0.4704	nac
Week 25	105	1.704 ± 0.4806		1.769 ± 0.6066	nac
Change at Week 25	105	−0.761 ± 0.5805	99	−0.711 ± 0.5850	nac
Treatment difference (LS-means) [confidence interval]	−0.0693 [-∞, 0.0692]
AUC of serum phosphorus (mmol/L × days)b	122	298.935 ± 72.0315	122	323.914 ± 81.2415
Treatment difference (LS-means) [confidence interval]	−24.5264 [−41.1978, −7.8550]				0.0042
No. of visits (N) target sP (≤ 1.78 mmol/L) reachedb	122	4.91 ± 3.275	122	3.96 ± 3.363	0.0198
No. of visits (N) target sP (≤ 1.45 mmol/L) reachedb	122	2.65 ± 2.784	122	1.81 ± 2.420	0.0067
Time (days) to target sP (≤ 1.78 mmol/L)b	122	16	122	30	0.0018
Time (days) to target sP (≤ 1.45 mmol/L)b	122	57	122	140	0.0052

^a(PPS, N = 204).

^b(FAS, N = 244).

^cNot applicable.