Table 3.

International ascites club criteria for hepatorenal syndrome[37]

Cirrhosis with ascites

Serum creatinine > 1.5 mg/dL (> 133 μmol/L)

No improvement in serum creatinine (< 1.5 mg/dL) after at least 2 d with diuretic withdrawal, and volume expansion with intravenous albumin. The recommended dose is 1 g/kg of body weight per day up to a maximum of 100 g/d

Absence of shock

No current or recent treatment with nephrotoxic drugs

Absence of parenchymal kidney disease as indicated by proteinuria > 500 mg/d, microhematuria (> 50 red blood cells per high power field) and/or abnormal renal ultrasonography