Table 2.

Summary of the descriptors that were found to be useful in decision making in the RP model

Descriptor	Illustration
S_ssCH2	Sum descriptor for carbon with two single bonds.
Hbond Acceptor	Number of hydrogen bond acceptor
ADMET_CYP2D6_PROB	Prediction of CYP2D6 inhibition.
Area	Molecular surface area.
Dipole-mag	The strength and orientation behaviour of a molecule in an electrostatic field.
Hbond donor	Number of hydrogen bond donor
S_aaN	Sum descriptor for nitrogen with two aromatic bonds.