Table 1.

Summary of SCL annotation in UniProtKB.

Items	Description	No. of Protein Sequences	Dataset Size	%
A	Proteins with SCL annotation in UniProt database	274730	494762	55.52
B	Proteins in A with experimentally known SCL	55079	494762	11.13
C	Proteins in A with uncertain terms such as potential/probable/similarity	219651	494762	44.39
D	Proteins with GO annotation	461365	494762	93.24
E	Protein with SCL annotation in GO database	337762	494762	68.26
F	UniProt human entries with experimentally known SCL	6923	20274	34.14
G	UniProt human entries with uncertain terms such as potential/probable/similarity	7486	20274	36.92

Distribution of 494762 protein entries from UniProtKB/Swiss-Prot* database (version 57.9) according to their SCL annotation and GO database reference.

* The original number of UniProt protein entries was 510076. Of these, 15314 were annotated as "fragment" or contained less than 50 amino acids residues, hence, were removed from further consideration, i.e. 494762. Similarly, we considered only 20274 human protein entries out of 20334 sequences.