Table 1.

PTZ-induced seizure responses in chr 15 congenic strains

	B6	15P	15M	15D
Latency to myoclonus, s	333 ± 74	348 ± 99	320 ± 99	326 ± 80
Latency to generalized seizure, s	438 ± 108	450 ± 93	415 ± 91	400 ± 102
Fraction with maximal seizure	0.33	0.17	0.33	0.33

Latency values are means ± SD (n = 6 per group). Mice were tested with 1 injection of pentylenetetrazol (PTZ, 80 mg/kg sc) and observed for 45 min. Latencies were analyzed with ANOVA, and maximal seizure responses were analyzed with Fisher's exact test. No statistically significant differences were obtained.