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Effects of mATP, NMS, and TTX on EFS contraction in wild-type and M2 KO bladders at 8 to 24 weeks after vehicle or STZ treatment. Inhibition of neurogenic contraction was measured in denuded (a) and intact (b) urinary bladder at 8 to 9 weeks and in denuded (c) and intact (d) bladder at 20 to 24 weeks after treatment. Mean values ± S.E.M. from 3 to 10 experiments are shown.
