Fig. 2.

Time course of METH-induced alterations in VMAT2 (A) and GFAP immunoreactivity (B). Rats received four injections of METH (7.5 mg/kg s.c. per injection; 2-h intervals) or saline vehicle (1 mg/kg s.c. per injection; 2-h intervals) and were sacrificed 24, 48, or 72 h later. Molecular masses (kDa) are indicated adjacent to the representative blot. Columns represent the means and vertical lines indicate 1 S.E.M. determinations in 5 to 10 rats. *, values different from saline-treated controls (p ≤ 0.05).