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. 2010 Oct;335(1):140–148. doi: 10.1124/jpet.110.169540

Fig. 1.

Fig. 1.

Effect of plasma infusion from hLCAT-Tg mice on lipids in LCAT-KO mice. Heat-inactivated plasma (control; open bars) or fresh (LCAT; solid bars) plasma (220 μl) from hLCAT-Tg mice, containing 3300 units of LCAT, was injected intravenously into LCAT-KO mice (n = 5). Plasma from the treated mice was collected at the indicated times and measured for total cholesterol (A) or CE (B). Data represent mean ± S.D. (n = 5). **, p < 0.001; ***, p < 0.0001, LCAT versus control group. LCAT activity after plasma infusion in LCAT-KO mice was measured (C) at the indicated times after the plasma infusion. Results are expressed as the percentage of first time point (5 min) after treatment. Results are the mean ± 1 S.D. of five replicates.