Table 1.
Transcript abundance in sinoatrial node and right atrial appendage
| Transcript | SAN | RAA | n |
|---|---|---|---|
| TnIS-S* | 0.8 ± 0.0 | 0.3 ± 0.0 | 28 |
| TnIS | 86.2 ± 0.1 | 15.6 ± 0.3 | 48 |
| TnIC | 19.8 ± 0.2 | 90.4 ± 0.2 | 42 |
| Kv1.1 | 88.1 ± 0.1 | 27.5 ± 0.1 | 28 |
| Kv1.2 | 49.4 ± 0.2 | 15.0 ± 0.1 | 9 |
| Kv1.3 | 31.0 ± 0.1 | 24.5 ± 0.0 | 9 |
| Kv1.4 | 87.2 ± 0.2 | 68.8 ± 0.3 | 9 |
| Kv1.5 | 90.9 ± 0.3 | 100.0 ± 0.2 | 9 |
| Kv1.6 | 20.8 ± 0.3 | 10.0 ± 0.1 | 6 |
| Kv2.1 | 49.8 ± 0.1 | 49.7 ± 0.3 | 6 |
| Kv2.2 | 21.2 ± 0.5 | 23.1 ± 0.2 | 6 |
| Kv3.1 | 12.3 ± 0.1 | 6.0 ± 0.1 | 6 |
| Kv3.2 | 10.0 ± 0.4 | 4.6 ± 0.1 | 6 |
| Kv3.3 | 9.5 ± 0.5 | 7.2 ± 0.2 | 6 |
| Kv3.4 | 5.4 ± 0.6 | 4.2 ± 0.1 | 6 |
| Kv4.1 | 15.8 ± 0.1 | 6.9 ± 0.1 | 6 |
| Kv4.2 | 50.0 ± 0.6 | 21.3 ± 0.7 | 6 |
| Kv4.3 | 34.1 ± 0.8 | 13.2 ± 0.3 | 6 |
| Kv5.1 | 15.6 ± 0.2 | 78.0 ± 0.5 | 10 |
| Kv6.1 | 12.9 ± 0.3 | 4.6 ± 0.1 | 6 |
| Kv7.1 | 55.9 ± 0.1 | 11.3 ± 0.2 | 6 |
| Kv10.1 | 25.4 ± 0.2 | 8.9 ± 0.1 | 6 |
| mink | 28.1 ± 0.2 | 11.2 ± 0.2 | 6 |
| Kv11.1 | 36.8 ± 1 | 10.6 ± 0.3 | 6 |
| Kv11.2 | 19.6 ± 0.6 | 16.8 ± 0.1 | 6 |
| Kv11.3 | 21.8 ± 0.2 | 7.1 ± 0.1 | 6 |
| HCN1 | 49.2 ± 0.3 | 10.6 ± 0.5 | 4 |
| HCN2 | 28.0 ± 0.7 | 6.9 ± 0.3 | 4 |
| HCN3 | 9.4 ± 0.2 | 2.0 ± 0.2 | 4 |
| HCN4 | 49.1 ± 0.7 | 4.4 ± 0.6 | 4 |
| Cav1.2 | 40.6 ± 0.5 | 8.2 ± 0.7 | 4 |
| Cav3.1 | 83.9 ± 1.4 | 22.2 ± 1.1 | 4 |
| Cav3.2 | 70.2 ± 1.8 | 26.6 ± 0.9 | 4 |
| Nav1.1 | 27.5 ± 1.1 | 38.1 ± 1.1 | 4 |
| Nav1.3 | 21.2 ± 1.4 | 27.7 ± 0.9 | 4 |
| Nav1.4 | 7.7 ± 0.8 | 53.0 ± 1.8 | 4 |
| Nav1.5 | 54.9 ± 0.2 | 48.9 ± 1.2 | 4 |
| Nav1.8 | 29.5 ± 0.1 | 25.8 ± 0.9 | 4 |
| Nav1.9 | 12.4 ± 0.6 | 29.7 ± 1.2 | 4 |
Values [in arbitrary relative fluorescence units, normalized to 100 (the value obtained from Kv1.5 in right atrial appendage)] are means ± SE; n = no. of sections scanned. Sections were probed by fluorescence in situ hybridization (FISH) and scanned as described in materials and methods. TnIS, TnIC, slow and cardiac troponin I, respectively; TnIS-S*, sense probe (negative) control; SAN, sinoatrial node, RAA, right atrial appendage. To highlight variability between animals, only 1 section per heart per transcript is included in this table.