Table 2.
Genes in risk loci shared by autoimmune or inflammatory diseases
| Gene | PsA | CD | UC | Asthma | MS | AD | RA | SLE | AS | T1D | CeD | T2D |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IL12B | X | X | X | X | X | |||||||
| 5q31 | X | X | X | X | ||||||||
| TNFAIP3 | X | X | X | X | ||||||||
| IL23R | X | X | X | |||||||||
| IL2/IL21 | X | X | X | X | X | X | X | X | ||||
| COG6 | X | |||||||||||
| PTPN22 | X | X | X | |||||||||
| ADAM33 | X | |||||||||||
| CDKAL1 | X | X |
PsA: Psoriatic arthritis; CD: Crohn’s disease, UC: Ulcerative Colitis; MS: multiple sclerosis; AD: Atopic dermatitis; RA: Rheumatoid arthritis; SLE: Systemic lupus erythematosus; AS: Ankylosing spondylitis; T1D: Type 1 diabetes; CeD: Coeliac disease; T2D: Type 2 diabetes