Table 1.

Nuclear morphological abnormalities in primary fibro-blasts with LMNA mutations as compared to a normal control (82–6, wt)

Cell line	LMNA mutation	Nuclear contour ratio	P (t test)	P (ftest)
82–6	wt	0.847 ±0.057	NA	NA
VGS1010	Pro485Arg	0.817±0.050	0.017	0.635
PORTU8010	Argl33Leu	0.788 ±0.100	<0.0001	0.031