Table 1. Distribution of Radioactive [¹⁸F]Lymphoseek 3 in Mice That Were Sacrificed 80 min following Injection^a.

	percent [18F]3 activity extracted in the sentinel node	Lymphoseek in the sentinel or popliteal lymph node (pmol) (percent of detected nodal Lymphoseek)	Lymphoseek flow-through to the distal or lumbar node (pmol) (percent of detected nodal Lymphoseek)
1 nmol Lymphoseek injection	87 ± 7%	3.0 ± 0.9 (91%)	0.3 ± 0.1 (9%)
11 nmol Lymphoseek injection	74 ± 7%	40 ± 15 (83%)	8 ± 3 (17%)
t test (one-tailed two-sample unequal variance)	P = 0.022		P = 0.033

^aScintigraphy data from six mice were obtained per injected Lymphoseek dose (12 mice total). The percent activity extracted is defined as the difference in counts between the sentinel and distal lymph nodes minus the sum of counts in the sentinel and distal lymph nodes [(counts_popliteal − counts_lumbar)/(counts_popliteal + counts_lumbar)]. The percent of detected nodal Lymphoseek is defined as the amount of Lymphoseek in the lumbar lymph node divided by the sum of the Lymphoseek in both the popliteal and lumbar lymph nodes. Error = σ/(n = 6)^1/2.