Table 3.

Association of SNPs in BCHE with cholinesterase activity.

SNP	Positiona	HWE p-value	MAF	Unadjusted p-values				FDR p-values (dominant)
				General	Additive	Dominant	Recessive
rs1803274	166,973,974	0.59	0.1	0.24	0.092	0.10	0.48	—
rs2668207b	166,976,418	0.4	0.34	0.0044	0.0048	0.00098	0.51	0.15
rs2686409	166,978,094	0.5	0.14	0.032	0.016	0.052	0.025	—
rs3863086	166,983,379	1	0.013	ND	0.55	0.55	ND	—
rs2668196	166,985,403	0.78	0.27	0.0073	0.016	0.0023	0.93	0.18
rs1355538	166,987,871	0.21	0.38	0.0088	0.017	0.0023	0.53	0.18
rs4680662	166,999,244	0.65	0.27	0.012	0.022	0.0039	0.93	0.24
rs12487357	167,004,510	0.67	0.21	0.17	0.15	0.075	0.88	—
rs4680663	167,015,102	1	0.036	ND	0.058	0.058	ND	—
rs2048493b	167,026,996	0.5	0.34	0.0026	0.0011	0.00068	0.12	0.15
rs4680607	167,036,281	0.9	0.1	0.021	0.027	0.088	0.011	—
rs1126680	167,037,819	1	0.015	ND	0.45	0.45	ND	—

Abbreviations: MAF, minor allele frequency; NCBI, National Center for Biotechnology Information; ND, cell values were too small for p-values to be determined.

^aNucleotide position is based on chromosome 3, NCBI Build 36 (http://www.ncbi.nlm.nih.gov/).

^bSNPs with strongest observed association.