Table 1. Summary of recent studies of human enterovirus 71 (HEV71) phylogeny.
| Reference | Gene/ regiona | No. of nucleotides sequenced | No. of new strains (source, time) |
|---|---|---|---|
| AbuBakar et al., 1999 (20) |
5′ UTR |
440 |
13 (Malaysia, 1997) |
| Brown et al., 1999 (21) |
VP1 |
891 |
113 (several countries, 1970–1998) |
| Shimizu et al., 1999 (15) |
VP4/VP2 |
420 |
29 (Malaysia and Japan, 1997; Taiwan, 1998; 5 others (Bulgaria, Hungary, Japan, Taiwan, USA), 1973–1980) |
| Wang et al., 2000 (16) |
5′ UTR |
681 |
36 (Taiwan, 1998) |
| Shih et al., 2000 (17) |
VP1 |
>500 |
16 (Taiwan, 1998) |
| Singh et al., 2000 (18) |
VP1 |
341 |
20 (Singapore, Japan, and Peninsular Malaysia, 1997–1998) |
| Chu et al., 2001 (19) |
VP4 |
207 |
20 (Taiwan, 1998); 3 (Taiwan, 1986) |
| McMinn et al., 2001 (22) |
VP1 |
891 |
66 (Sarawak, Singapore, and Perth, 1997–2001) |
| Wang et al., 2002 (11) | 5′ UTR VP1 | 648 841 | 26, 3, and 19 strains (Taiwan, 1998, 1999, and 2000) were sequenced in the 5′ UTR; 12, 2, and 19 strains (same 3 years) were sequenced in VP1 |
aUTR, untranslated region.