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. 2010 Oct 20;5(10):e13521. doi: 10.1371/journal.pone.0013521

Figure 1. IFNα potently inhibits HIV-1 replication in MDM but not PBMC/MDDC.

Figure 1

(a) MDM, PBMC and MDDC were treated with 500 IU/ml IFNα 24 hr prior to challenge with HIV-1 89.6. Culture supernatants were assayed after 4 days for levels of RT by ELISA (pg/ml). (b & c) MDM were treated with 500 IU/ml IFNα or β 24 hr prior to infection with a panel of replication competent HIV-1. Infected foci were counted after 4 days. Fold reduction is the ratio of FFU/ml of no IFN compared to IFNα treated cells. Error bars represent SD of one representative experiment.