Figure 2. A strong negative correlation is observed between peripheral mononuclear cell proliferation and AHL lipophilicity.

The IC₅₀ for human peripheral mononuclear cell proliferation (PBMCs) isolated from three donors (* denotes n = 2) in the presence of AHLs of chain lengths between 8 and 14 carbons (values obtained from [18]) exhibit a strong negative correlation (Pearsons r = −0.895, p = 0.016) against the predicted octanol/water partition coefficient (LogP) for each compound (calculated using ACD/i-Lab LogP algorithm 12.0). n = 3, ±SEM. Projected LogP are given in Table 1.