Table 1.

Pathways significantly over-represented in muscle samples of Weddell seals hybridized on Human U133 expression array.

Map	Map Folders	Cell process	p-Value	Objects
				present	total
Cytoskeleton remodeling	Regulatory processes/Cytoskeleton remodeling		1.74E-10	41	83
Cytoskeleton remodeling, TGF, WNT and cytoskeletal remodeling	Regulatory processes/Cytoskeleton remodeling		2.60E-07	40	98
Translation, Regulation of translation initiation	Regulatory processes/Translation	translation	2.89E-07	14	19
* Cytoskeleton remodeling, Role PKA in cytoskeleton reorganisation	Protein function/Kinases Regulatory processes/Cytoskeleton remodeling	protein kinase cascade	6.50E-07	18	30
* Signal transduction, PKA signaling	Protein function/G-proteins/GPCR Protein function/Kinases Protein function/Second messenger	second-messenger-mediated signaling, protein kinase cascade, G-protein coupled receptor protein signaling pathway	1.27E-06	15	23
Cell adhesion, Histamine H1 receptor signaling in the interruption of cell barrier integrity	Protein function/G-proteins/GPCR Regulatory processes/Cell adhesion	G-protein coupled receptor protein signaling pathway, cell adhesion	1.54E-06	20	37
Cytoskeleton remodeling, Regulation of actin cytoskeleton by Rho GTPases	Protein function/G-proteins/RAS-group Regulatory processes/Cytoskeleton remodeling	small GTPase mediated signal transduction	1.98E-06	14	21
Transcription, Formation of Sin3A and NuRD complexes and their role in transcription regulation	Regulatory processes/Transcription	transcription	2.81E-06	15	24
Development, Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis	Protein function Second messenger Protein function Transcription factors Regulatory processes Development Myogenesis	second-messenger-mediated signaling, transcription, response to extracellular stimulus	4.22E-06	22	45

Only first 10 pathways shown, the complete table is given is Additional File 1. The analysis is performed using GeneGo MetaCore software.