Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of pHPMA-crosslinker coupling reactions
| polymer conjugate | crosslinker | crosslinker contenta (μmol/g) | conversion (%) | remaining hydrazideb (μmol/g) | conversion (%) |
|---|---|---|---|---|---|
| 13 | PMCA | 373.0 ± 21.2 | 141.8 ± 8.1 | 19.5 ± 0.1 | 92.6 ± 4.3 |
| 14 | BMCA | 248.9 ± 8.1 | 94.6 ± 3.1 | 18.6 ± 0.1 | 92.9 ± 5.6 |
| 15 | APM | 166.7 ± 14.5 | 69.8 ± 6.1 | 90.9 ± .1 | 62.0 ± 1.9 |
n=4 for all measurements
determined by crosslinker optical absorbance
determined by TNBSA assay
