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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Cancer Treat Rev. 2010 Jun 8;37(1):63–74. doi: 10.1016/j.ctrv.2010.05.001

Figure 4.

Figure 4

Hematoxylin and eosin stained section (at x 200 magnification) of KHT sarcoma treated with OXi4503 (25 mg/kg). The post-treatment necrotic tumor is defined by the double-headed arrow while the two- or three-cell layer of the viable tumor rim is shown with a single-headed arrow. Preserved muscle (*) and blood vessels (black arrowheads) are clearly evident in the surrounding, unaffected tissue (Siemann DW, unpublished results).