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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Inflamm Bowel Dis. 2011 Feb;17(2):503–515. doi: 10.1002/ibd.21391

Figure 7.

Figure 7

(A) ELISA for PIP3 concentration (pMol/106 cells) in bone marrow derived-neutrophil treated with 10–50μM of curcumin 5 minutes prior to a 30-second stimulation with MIP-2 (20ng/ml). (B) Western blot analysis of phospho-AKT (Ser473) or to phospho-p44/42 MAPK (Thr202/Tyr204) in PMNs treated with 10–50μM of curcumin 5 minutes prior to a 30-second stimulation with MIP-2 (20ng/ml). Total AKT and total ERK were evaluated as loading control. * p≤0.05 curcumin/MIP-2 vs. control or MIP-2 alone (ANOVA followed by Fisher PLSD post-hoc test). (C) Densitometric analysis of AKT and (D) ERK phosphorylation in response to MIP-2 with or without 10–50μM curcumin.