Table 1.
Summary of recent GWAS of hypertension and/or blood pressure.
| Publication date | Phenotype | Discovery sample | Discovery and replication meta-analysis | |||||
|---|---|---|---|---|---|---|---|---|
| N | OR/beta | Lowest P-value | N | OR/beta | P-value | |||
| Levy et al. [66] | Sept-07 | DBP | 1233 | — | 3.31 × 10−6 | — | — | — |
| SBP | 1260 | — | 1.69 × 10−6 | — | — | — | ||
| *Wang et al. [67] | Jan-09 | SBP | 542 | — | 7.6 × 10−5 | 7125 | 1.9 | 1.6 × 10−7 |
| Org et al. [68] | Mar-09 | hypertension | 364/596 | 0.49 | 2.34 × 10−6 | 3808/4334 | 0.78 | 1.39 × 10−6 |
| Cho et al. [69] | May-09 | SBP | 8842 | −1.309 | 9.1 × 10−7 | 16703 | −1.064 | 1.3 × 10−7 |
| Adeyemo et al. [70] | Jul-09 | DBP | 8842 | −0.882 | 1.2 × 10−6 | 16703 | −0.63 | 3.0 × 10−6 |
| SBP | 1017 | — | 4.72 × 10−8 | — | — | — | ||
| DBP | 1017 | — | .448 | 1997 | — | .162 | ||
| hypertension | 509/508 | 0.58 | 5.10 × 10−7 | 875/1122 | — | .009 | ||
*Observed an SNP with a lower P-value but did not report on it as situated in gene desert.
—Value not reported (or in the case of meta-analysis replication not attempted).