Table 2.
Baseline Demographic Characteristics
| |
DT |
BT |
|
|---|---|---|---|
| Number | 70 | 76 | P value |
| Age (years) | |||
| Mean (SD) | 64.0 (8.2) | 63.7 (7.4) | 0.821 |
| 95% CI | 62.1–66.0 | 62.1–65.4 | |
| Min | 50 | 51 | |
| Max | 70 | 76 | |
| MAPa (mmHg) | |||
| Mean (SD) | 89.6 (6.8) | 89.0 (6.2) | 0.619 |
| 95% CI | 87.9–91.2 | 87.6–90.4 | |
| Min | 78.3 | 77.6 | |
| Max | 100.0 | 100.0 | |
| Mean IOP (mmHg) | |||
| Mean (SD) | 22.8 (1.2) | 22.7 (1.2) | 0.631 |
| 95% CI | 22.5–23.1 | 22.5–23.0 | |
| Min | 20.7 | 20.5 | |
| Max | 25.7 | 25.7 | |
| Systemic medicationsb | |||
| High blood pressure | 12 (17.1%) | 16 (21.1%) | 0.675 |
| Cardiovascular disease | 3 (4.3%) | 5 (6.6%) | 0.721 |
| Arthrosis | 9 (12.9%) | 5 (6.6%) | 0.263 |
Abbreviations: DT, dorzolamide/timolol; BT, brinzolamide/timolol; SD, standard deviation; 95% CI, 95% confidence interval; MAP, mean arterial pressure; IOP, intraocular pressure.
P values were calculated comparing the parameters at baseline between the two study groups (one-way ANOVA test); P values were considered statistically significant if lower than 0.05.
a
MAP = DBP + ⅓ (SBP – DBP).
b
Fisher's exact test. P values were considered statistically significant if lower than 0.05.