Table 2.
Genotypic and allelic distributions of NOS3 polymorphisms for cases and controls.
| Cases, n (%) | Controls, n (%) | P-value | |
|---|---|---|---|
| T786C | |||
| TT | 69 (30.4) | 101 (35.0) | |
| TC | 118 (52.0) | 148 (51.2) | |
| CC | 40 (17.6) | 40 (13.8) | .37(a) |
| T alleles | 246 (55.4) | 350 (60.6) | |
| C alleles | 198 (44.6) | 228 (39.4) | .12(b) |
|
| |||
| Intron 4a/b | |||
| 4b/b | 165 (72.4) | 190 (62.7) | |
| 4a/b | 59 (25.9) | 101 (33.3) | |
| 4a/a | 4 (1.7) | 12 (4.0) | .04(a) |
| b alleles | 389 (85.3) | 481 (79.4) | |
| a alleles | 67 (14.7) | 125 (20.6) | .03(b) |
|
| |||
| G894T | |||
| GG | 99 (43.4) | 135 (44.7) | |
| GT | 95 (41.7) | 130 (43.1) | |
| TT | 34 (14.9) | 37 (12.2) | .67(a) |
| G alleles | 283 (63.5) | 400 (66.2) | |
| T alleles | 163 (36.5) | 204 (33.8) | .39(b) |
(a) P-value for the comparison of genotypic distribution. (b) P-value for the comparison of the allelic distribution.