Figure 5.

MET during somitogenesis. (A) Model showing the molecular pathways involved in intersomitic border formation and somite epithelialization in amniotes. Anterior to the left. (B) Somites (dashed box) appear in a rostro-caudal fashion at the dorsal side of a ten somite-stage mouse embryo. (C) Scanning electronic micrograph of 4 somitic blocks from a ten somite-stage mouse embryo. (D) Confocal image showing the mesenchymal core surrounded by epithelium in an epithelized somite. Phalloidin (red) labels the actin cytoskeleton and Hoechst (blue), the nuclei.