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Darbepoetin and neutrophil accumulation in infarcted myocardium. Top: neutrophil numbers in the infarct zone were determined by counting immunopositive neutrophils in the infarct zone 24 h after reperfusion. Results are mean ± SEM of five mice in each group. *P < 0.05 from infarct zone of vehicle-treated group. Bottom: photomicrographs of neutrophils accumulating in the infarct zone of mice treated with vehicle or darbepoetin (30 µg·kg−1). Bar represents 100 µm.
