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. Author manuscript; available in PMC: 2010 Oct 21.
Published in final edited form as: J Biol Chem. 2007 Dec 18;283(8):5069–5080. doi: 10.1074/jbc.M708734200

Fig. 1. Binding of antifungal azole drugs to CYP130.

Fig. 1

The concentration dependence of econazole (A), clotrimazole (B), miconazole (C) and ketoconazole (D) binding deduced from the difference absorption changes obtained from the titration of CYP130 (2.5 µM) with increasing concentrations of the inhibitor. The structure of the inhibitor is shown in each panel.