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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Aging Cell. 2010 Oct;9(5):851–867. doi: 10.1111/j.1474-9726.2010.00616.x

Figure 8.

Figure 8

PTH attenuates the inhibitory effect of oxidative stress on β-catenin/Tcf-mediated transcription. Luciferase activity (relative light units, RLU) in UAMS-32P or OB-6 cells transfected with a Tcf-luc reporter construct after pretreatment for 1 hour with PBS (veh) or 50 nM PTH, then with saline (−), 50 ng/ml Wnt3a (50 ng/ml), 100 μM H2O2, or the combination of Wnt3a and H2O2 for 24 h. Bars represent the mean of triplicate determinations. * p<0.05 vs. respective vehicle control, ‡ <0.05 vs. vehicle alone, # p<0.05 vs. Wnt3a alone by one-way ANOVA.