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Binding of parental TK04-190Asp and mutant TK04-190Ala viruses to plasma membrane preparations (PMP) from human, pig and turkey primary tracheal/bronchial epithelial cells. Both viruses bound with similar efficiency to PMP from HAEC and PEC but not TEC (P-value < 0.02) at high virus titer (64 HA). Nonetheless, 190Ala virus showed decreased binding efficiency (P-value <0.04 and <0.019 for HAEC and PEC respectively) to all PMP at lower titers.
