Table 3.
Estimated haplotype frequencies and association significance
| Haplotype* | Haplotype frequency(%) | X2 | p value | Odds Ratio (95%CI) | |||||
|---|---|---|---|---|---|---|---|---|---|
| rs6452526 | rs2662238 | rs963248 | rs35268 | rs2386275 | CRC | SZ | |||
| T | A | 63.97(13.0) | 98.00(20.2) | 8.251 | 0.004 | 0.61(0.43-0.86) | |||
| C | G | 415.97(84.2) | 386.00(79.8) | 8.251 | 0.004 | 1.65(1.17-2.33) | |||
| G | C | 40.64(8.1) | 61.29(12.5) | 5.118 | 0.024 | 0.62(0.41-0.94) | |||
| T | A | G | T | A | 18.46(5.2) | 45.45(10.2) | 6.693 | 0.010 | 0.48(0.28-0.85) |
| T | A | G | C | A | 5.22(1.5) | 20.07(4.5) | 5.918 | 0.015 | 0.32(0.12-0.84) |
| C | G | A | T | G | 54.49(15.2) | 36.21(8.2) | 10.445 | 0.001 | 2.07(1.32-3.24) |
*Haplotypes were omitted from analysis if the estimated haplotype probabilities were less than 5%
CI = confidence interval, CRC = colorectal cancer, SZ = schizophrenia.