Table 1.
Results of recent clinical experience with Interstitial brachytherapy with more than 5 years follow up
| Author | No of cases | Follow up interval (years) | Dose rate/pt no | Scheme | Total dose (Gy) | 5-year LR (%) | Good/Excellent cosmesis |
|---|---|---|---|---|---|---|---|
| Strnad et al.[60] | 274 | 5.25 | PDR/HDR | PDR = 0.6 Gy/hr HDR = 4 Gy x8 |
PDR = 50 Gy HDR = 32 Gy |
2.9% | 90% |
| Antonucci et al. [59] | 199 | 9.6 | LDR/HDR | LDR 0.52 Gy/h × 96 hours HDR = 4 Gy x8 HDR = 3.4 Gyx10 |
LDR = 50 Gy HDR = 32 Gy HDR = 34 Gy |
5% | 99% |
| Johansson et al.[61] | 50 | 7.2 | PDR | 50Gy/5 | 50 | 4% | 56% |
| Arthur et al.[62] | 99 | 7 | LDR/HDR | LDR = 3.5 -5 days HDR = 3.4 × 10 |
45 Gy (LDR) 34 Gy (HDR |
4% | n/a |
| Polgar et al.[63] | 128 | 6.8 | HDR | 5.2 × 7 | 36.4 Gy | 4.7% | 77% |
| King et al [64] | 51 | 6.25 | LDR/HDR | LDR = 4 days 4 Gyx8 |
45 Gy (LDR) 32 Gy (HDR) |
3.9% | 75% |
| Otto et al. [65] | 274 | 5.25 | PDR/HDR | PDR 5 days, 0.6 Gy/hr HDR = 4 Gyx8 |
49.8 Gy (PDR) 32 Gy (HDR) |
2.9% | 92% |
| Polgar et al.[58] | 45 | 11.1 | HDR | 4.33 × 7 5.2 × 7 |
30.3 Gy 36.4 Gy |
4.4% | 78% |
LR = local recurrence, HDR = high dose rate, LDR = low dose rate, PDR = pulsed dose rate, n/a = data not available