Table 4.
Comparison reductions in ARS scores after MPH treatment in ADHD subjects according to genotypes of the -3081(A/T) polymorphism
| Genotype | Changes in ARS scores | |||||
|---|---|---|---|---|---|---|
| IA | p-value | Hy/Imp | p-value | Total | p-value | |
| A/A | 5.4 (4.3) | 0.54 | 4.6 (4.1) | 0.12 | 8.4 (7.6) | 0.10 |
| A/T | 6.2 (4.9) | 6.3 (4.5) | 12.1 (8.8) | |||
| T/T | 7.2 (6.6) | 7.8 (7.2) | 14.7 (12.6) | |||
| A/A | 5.4 (4.3) | 0.38 | 4.6 (4.1) | 0.09 | 8.4 (7.6) | 0.06 |
| A/T + T/T | 6.5 (5.4) | 6.7 (5.4) | 12.8 (10.0) | |||
ARS, ADHD Rating Scale; IA, inattentive subscale; Hy/Imp, hyperactivity/impulsivity subscale
All values are mean (± S.D.)