Table 2.

Effects of heat exposure (42°C for 80 min) plus 25 min room temperature (24°C) exposure on the neuronal damage score values of corpus striatum from normal saline-treated, dexamethasone(DXM), HES or the combined agent (DXM+HES)-treated rats^a.

Treatment	Score of neuronal damage (0-3)
	striatum
1. Normal saline (1 ml/kg, i.v.)-treated rats at 24°C	0 (0, 0.75)
2. Normal saline (1 ml/kg, i.v.)-treated rats at 42°C	2 (2, 2.25)b
3. DXM (4 mg/kg, i.v.)-treated rats at 42°C	2 (2, 2)b
4. HES (10%, 11 ml/kg, i.v.)-treated rats at 42°C	1 (0.25, 1)c
5. DXM (4 mg/kg, i.v.)+HES (10%, 11 ml/kg, i.v.)-treated rats at 42°C	1 (0, 1)c

^aValues are means ± S.E. of 8 rats per group followed by median with Q₁and Q₃ in parenthesis. For determination of neuronal damage score animals were killed after 80 mins heat exposure plus 25 mins room temperature exposure. The data were evaluated by a Wilcoxon signed rank test followed by Mann-Whitney test.

^bP < 0.05, significance of difference from corresponding values (treatment 1, control rats).

^cP < 0.05 significance of difference from corresponding values (treatment 2).