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. 2010 Oct 8;9:273. doi: 10.1186/1475-2875-9-273

Table 2.

Whole blood concentrations of mefloquine on Day-0 (pre-treatment), days 7, 14, 21, 28, 35 and 42 of treatment in patients with sensitive response and recrudescence.

Day of treatment Sensitive response Recrudescence response

N Mean (95%CI)* or Median (95% CI)** N Mean (95%CI)* or Median (95% CI)**
Day 0** 90 0 (0-1,714) 36 0 (0-92)

Day 1* 36 1,411 (1,216-1,605) 12 1,345 (1,067-1,624)

Day 7* 22 1,055 (806-1,304) 9 754 (541-968)

Day 14* 21 659 (426-893) 10 421 (181-660)

Day 21* 15 416 (258-575) 11 359 (230-488)

Day 28* 13 233 (158-307) 8 288 (146-329)

Day 35* 12 145 (96-195) 6 179 (41-317)

Day 42** 19 19 (5-163) 9 13 (0-49)