Table 3.

Five-Year Endothelial Cell Density (ECD) in Eyes with a Successful Transplant Using Baseline Specular Microscopy Reading Center–Determined ECD (N = 229)

Donor Age	N	Baseline ECD [Median (Interquartile Range)] (cells/mm2)	5-Year ECD [Median (Interquartile Range)] (cells/mm2)	% Change from Baseline to 5 Years* [Median (Interquartile Range)]
Overall	229	2668 (2432–2892)	778 (566–1336)	−70% (−77% to −50%)
66.0–<76.0	67	2562 (2414–2798)	649 (522–1336)	−75% (−79% to −53%)
12.0–<66.0	162	2679 (2446–2905)	819 (587–1342)	−69% (−77% to −49%)
56.0–<66.0	75	2681 (2446–2938)	748 (563–1127)	−71% (−79% to −56%)
41.0–<56.0	60	2618 (2426–2824)	797 (582–1440)	−69% (−76% to −43%)
12.0–<41.0	27	2812 (2562–3062)	1074 (786–1624)	−64% (−70% to −47%)

^*Endothelial cell density at 5 yrs minus ECD at baseline divided by ECD at baseline and multiplied by 100%. A negative number indicates loss of cells.